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British researchers discover new ways to treat tuberculosis

Number of visits: Date:2014-10-30 10:01:09

LONDON, April 26 - British researchers recently reported that they have a new understanding of the pathogenesis of tuberculosis in the lung tissue damage causes an enzyme was found to play a key role in which, so you can suppress this the action of enzymes to treat tuberculosis. This discovery may soon translate into actual therapies.

British researchers at Imperial College in the United States the new issue of "Journal of Clinical examination," the report said, they check for some TB patients showed higher enzyme content patient called MMP-1's. The researchers then cultured human cells in a test tube, allowed infected with TB bacilli, the results also found that one of the enzyme content increased. The researchers also carried out animal experiments, the results are displayed in the mice, this will lead to increased enzyme levels similar to human patients with lung damage.

The researchers believe that if we can use drugs inhibiting this enzyme, it may be becoming a new way to treat tuberculosis. This study has demonstrated in vitro on cultured human cells infected with M. tuberculosis, the ability to use some of the existing drugs to inhibit the role of this enzyme.

The researchers said Paul Elkington, tuberculosis therapy is not much progress in recent decades, this study reveals a novel therapeutic approach, particularly important, maybe you can use some of the existing drugs.

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, recurrent symptoms of cough, fatigue, etc., severe hemoptysis or even death, in the history has long been considered incurable. After the 20th century, the advent of antibiotics related to tuberculosis treatment becomes easier, but with the gradual increase of bacterial resistance, tuberculosis worldwide comeback trend.

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